3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid

3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid - Names and Identifiers

Name	3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid
Synonyms	AKOS BRN-0547 3-Fluoro-4-(Methoxycarbonyl)Ph METHYL 4-BORONO-2-FLUOROBENZOATE methyl 4-borono-2-fluorobenzoate 3-Fluoro-4-(methoxycarbonyl)phenylbonoic 3-fluoro-4-methoxycarboxyphenylboronic acid 3-FLUORO-4-METHOXYCARBONYLPHENYLBORONIC ACID 3-FLUORO-4-METHOXYCARNONYLPHENYLBOEONIC ACID 3-Fluoro-4-Methoxycarbonylphenylboronic Acid 3-FLUORO-4-METHOXYCARBONYLBENZENEBORONIC ACID 3-Fluoro-4-(methoxycarbonyl)phenylboronic acid 3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid 1-Chloro-2-isocyanato-4-(trifluoromethyl)benzene Benzene, 1-chloro-2-isocyanato-4-(trifluoromethyl)- 3-Fluoro-4-(methoxycarbonyl)phenylboronic Acid (contains varying amounts of Anhydride)
CAS	505083-04-5
InChI	InChI=1/C8H3ClF3NO/c9-6-2-1-5(8(10,11)12)3-7(6)13-4-14/h1-3H

3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid - Physico-chemical Properties

Molecular Formula	C8H8BFO4
Molar Mass	197.96
Density	1.33±0.1 g/cm3(Predicted)
Melting Point	180-184°C
Boling Point	361.8±52.0 °C(Predicted)
Flash Point	92.2°C
Vapor Presure	0.423mmHg at 25°C
Appearance	Solid
pKa	6.61±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.487
MDL	MFCD04115665

3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing.
HS Code	29319090
Hazard Note	Irritant/Keep Cold
Hazard Class	IRRITANT

3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid - Introduction

3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid is an organic compound whose chemical formula is C9H8BFO4. The following is a detailed description of the properties, uses, preparation methods and safety information of the compound:

Nature:
-Appearance: 3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid is a white solid.
-Solubility: The compound is soluble in some organic solvents, such as methanol, ethanol and dichloromethane.
-Melting point: Its melting point range is 174-177 degrees Celsius.

Use:
- 3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid is an important organic synthesis intermediate, which can be used to synthesize pharmaceutically active or other organic compounds.
-It is often used as a ligand or reagent to participate in metal-catalyzed reactions, such as palladium-catalyzed coupling reactions.

Preparation Method:
-A common synthesis method is to obtain 3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid by reacting 4-methoxycarbonylphenylboronic acid with a fluorinating reagent under alkaline conditions.

Safety Information:
- 3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid is a relatively safe compound under general conditions.
-When handling the compound, wear appropriate personal protective equipment, such as chemical protective gloves and goggles, to prevent contact with skin and eyes.
-During storage and handling, avoid contact with harmful substances such as oxidants and strong acids to prevent reactions or accidents.
-If the compound is inhaled or ingestion, medical help should be sought immediately, and the safety data sheet of the compound should be provided to the doctor for reference.

Last Update：2024-04-09 15:17:58